Affymetrix GeneChip Rat Expression Array RAE230A [RAE230A]

Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes.

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.

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Effects of hyperglycaemia and genetic background differences on renal gene expression

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Transcription profiling of rat to investigate effects of hyperglycaemi and genetic background on gene expression

Effects of hyperglycaemia and genetic background differences on renal gene expression


Affymetrix:Protocol:Hybridization-Unknown

P-AFFY-6

Title: Affymetrix CEL analysis. Description:

Organs were rapidly dissected out and immediately snap frozen in liquid nitrogen and stored at -80°C until use.

Gene chip data were normalised by use of RMA quantile normalization. We used the RMA expression index, ignoring Mismatch (MM) values for background correction. A linear model for microarray data (LIMMA) was used to calculate significant differences between groups. To correct for multiple testing, we used the false discovery rate.

Transcription profiling of rat to investigate effects of hyperglycaemi and genetic background on gene expression

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