Co-evolution of Met amplification and Hgf overexpression mediate resistance to BRAF inactivation in mouse anaplastic thyroid cancers.

GSE118022

Mus musculus

24 Downloadable Samples

Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Submitter Supplied Information

Description

Affymetric arrays were performed on thyroid samples collected from GEMMs: normal thyroid, TPO-Cre/LSL-Braf (PTC), TPO-Cre/tetO-BRAF/LSL-rtTAiresGFP/p53-flox (ATC) and TPO-Cre/tetO-BRAF/LSL-rtTAiresGFP/p53-flox (recurrent tumors)

PubMed ID

29990309

Publication Title

Hgf/Met activation mediates resistance to BRAF inhibition in murine anaplastic thyroid cancers.

Total Samples

Submitter’s Institution

Memorial Sloan Kettering Cancer Center

Authors

Knauf JA, Luckett KA, Chen KY, Voza F, Socci ND, Ghossein R, Fagin JA

Source Repository

Gene Expression Omnibus (GEO)

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