Expression analysis upon NMNAT1 knockdown in MCF-7 cells

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GSE13458

Homo sapiens

10 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2), Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

NMNAT1 is a nuclear enzyme in the mammalian NAD+ salvage pathway. Expression microarray analysis was used to study the effect of NMNAT1 knockdown on gene expression in MCF-7 breast cancer cells.

PubMed ID

19478080

Publication Title

Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters.

Total Samples

Submitter’s Institution

UT Southwestern Medical Center

Authors

Zhang T, Berrocal JG, Frizzell KM, Gamble MJ, DuMond ME, Krishnakumar R, Yang T, Sauve AA, Kraus WL

Source Repository

Gene Expression Omnibus (GEO)

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