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GSE17007
Gene expression of Kit225 cells upon NC1153 treatment
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Homo sapiens
4 Downloadable Samples
Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)
Submitter Supplied Information
Description
NC1153 was shown to inhibit JAK3 tyrosine kinase. Lymphocytes survival depends on the integrity of STAT5, the primary downstream target of JAK3.
PubMed ID
20211620
Publication Title
Uncoupling JAK3 activation induces apoptosis in human lymphoid cancer cells via regulating critical survival pathways.
Total Samples
4
Submitter’s Institution
University of Debrecen
Authors
Nagy ZS
,
Ross JA
,
Rodriguez G
,
Bader J
,
Dimmock J
,
Kirken RA
Source Repository
Gene Expression Omnibus (GEO)
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