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Accession IconGSE21016

Genome-wide analysis of gene expression profiles in ITNK

Organism Icon Mus musculus
Sample Icon 12 Downloadable Samples
Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Submitter Supplied Information

Description
Analysis of gene expression profiles in Induced T-to-Natural Killer (ITNK), compared to DN3 parental T cells and IL-2-expanded NK cells (LAK). The hypothesis tested in the present study was that gene expression profiles of ITNK that were derived from DN3 T cells after deletion of Bcl11b were more similar to LAK, rather than DN3 T cells. Results provide important information of the ITNKs, such as canditate genes regulated by Bcl11b, up-regulated important genes expressed in NK cells, and down-regulated T cell genes.
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Total Samples
12
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Samples

Show of 12 Total Samples
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ITNK rep1 (4459290092_E)
itnk (dn3-derived t-to-nk cells)
ITNK rep4 (4459290113_B)
itnk (dn3-derived t-to-nk cells)
LAK rep3 (4459290092_C)
lak (il-2-expanded nk cells)
LAK rep4 (4459290092_D)
lak (il-2-expanded nk cells)
ITNK rep3 (4459290113_A)
itnk (dn3-derived t-to-nk cells)
DN3 rep4 (4459290113_F)
dn3 (parental t cells)
DN3 rep3 (4459290113_E)
dn3 (parental t cells)
LAK rep1 (4459290092_A)
lak (il-2-expanded nk cells)
DN3 rep1 (4459290113_C)
dn3 (parental t cells)
DN3 rep2 (4459290113_D)
dn3 (parental t cells)
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