Genome-wide analysis of time-dependent gene expression in SUM-225 cells treated with the HER-2-specific inhibitor CP724,714 for 45 hours

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GSE22955

Homo sapiens

7 Downloadable Samples

Illumina HumanRef-8 v3.0 expression beadchip, Illumina humanRef-8 v2.0 expression beadchip

Submitter Supplied Information

Description

Results of blocking the HER-2 oncogene kinase function in SUM-225 cells by treatment with CP724,714 and measuring gene expression as a function of time provides information as to what genes are regulated by HER-2 in this breast cancer cell line.

PubMed ID

21437235

Publication Title

Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.

Total Samples

Submitter’s Institution

Karmanos Cancer Inst., Wayne State University

Authors

Bollig-Fischer A, Dewey TG, Ethier SP

Source Repository

Gene Expression Omnibus (GEO)

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