Hypermethylation of miR-34b is associated with CREB overexpression and Myeloid Cell Transformation

Increased CREB levels and upregulation of its target genes expression resulted in increased myelopoiesis and colony formation.

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Pigazzi M, Manara E, Bresolin S, Tregnago C, Beghin A, Baron E, Giarin E, Cho EC, Masetti R, Rao DS, Sakamoto KM, Basso G