E.coli response to Antimicrobial Arylamides

GSE31140

Escherichia coli

17 Downloadable Samples

Affymetrix E. coli Genome 2.0 Array (ecoli2)

Submitter Supplied Information

Description

We treated logarithmically growing cultures of E.coli with a sub-lethal dose of an antimicrobial arylamide compound (PMX 10070) and Polymyxin B sulfate to measure transcriptional responses in an effort to understand mechanism of action

PubMed ID

21844313

Publication Title

Antibacterial mechanism of action of arylamide foldamers.

Total Samples

Submitter’s Institution

University of Pennsylvania, School of Medicine

Authors

Mensa B, Kim YH, Choi S, Scott R, Caputo GA, DeGrado WF

Source Repository

Gene Expression Omnibus (GEO)

GSM770871

E. coli control at time=60 min, rep 1

GSM770864

E. coli control at time=20 min, rep 3

GSM770879

E. coli Polymyxin B treatment at time=60 min, rep 3

GSM770875

E. coli PMX 10070 treatment at time=60 min, rep 2

GSM770865

E. coli PMX 10070 treatment at time=20 min, rep 1

GSM770874

E. coli PMX 10070 treatment at time=60 min, rep 1

GSM770870

E. coli Polymyxin B treatment at time=20 min, rep 3

GSM770872

E. coli control at time=60 min, rep 2

GSM770869

E. coli Polymyxin B treatment at time=20 min, rep 2

GSM770873

E. coli control at time=60 min, rep 3