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GSE35048Sirolimus induced phosphaturia
Rattus norvegicus
8 Downloadable Samples
Affymetrix Rat Gene 1.0 ST Array (ragene10st)Submitter Supplied Information
Description
Introduction: The kidney is the major arbiter of extracellular phosphate homeostasis. The vast majority of glomerular filtrated phosphate is reabsorbed in the proximal tubule. Posttransplant phosphaturia is common and aggravated by sirolimus immunosuppression. The cause of sirolimus induced phosphaturia however remains elusive.
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