Pdx1 maintains -cell identity and function by repressing an -cell program

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GSE52258

Mus musculus

15 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

To get a more complete picture of the transcriptional changes associated with Pdx1 loss in -cells, we conducted an mRNA microarray comparing normal islet -cells and a-cells to the reprogrammed cells from PKO mice.

PubMed ID

24506867

Publication Title

Pdx1 maintains β cell identity and function by repressing an α cell program.

Total Samples

Submitter’s Institution

University of Pennsylvania

Authors

Gao T, McKenna B, Li C, Reichert M, Nguyen J, Singh T, Yang C, Pannikar A, Doliba N, Zhang T, Stoffers DA, Edlund H, Matschinsky F, Stein R, Stanger BZ

Source Repository

Gene Expression Omnibus (GEO)

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