Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming

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GSE69295

Homo sapiens

18 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

The progesterone receptor specific gene targets were investigated in ovarian and breast cancer cell lines where FOXO1 was found to be a primary factor that cooperates with PR to activate cellular senescence genes (including p21) specifically in ovarian cells.

PubMed ID

26577046

Publication Title

Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming.

Total Samples

Submitter’s Institution

University of Minnesota

Authors

Diep CH, Knutson TP, Lange CA

Source Repository

Gene Expression Omnibus (GEO)

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