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GSE84205
mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors
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Homo sapiens
12 Downloadable Samples
Affymetrix Human Gene 1.0 ST Array (hugene10st)
Submitter Supplied Information
Description
mTOR and HDAC inhibitors induce cell death of malignant peripheral nerve sheath tumors (MPNSTs) in vitro, and in vivo
PubMed ID
28963352
Publication Title
mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.
Total Samples
12
Submitter’s Institution
Harvard Medical School - Brigham Women's Hospital
Authors
Malone CF
,
Emerson C
,
Ingraham R
,
Barbosa W
,
Guerra S
,
Yoon H
,
Liu LL
,
Michor F
,
Haigis M
,
Macleod KF
,
Maertens O
,
Cichowski K
Source Repository
Gene Expression Omnibus (GEO)
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