Identification of potential ABBV-075 responsive markers in human PBMCs - refine.bio

GSE89933

Homo sapiens

10 Downloadable Samples

Technology Badge Icon

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

To identify genes that are modulated by BET inhibitors in blood, we determined global gene expression changes in ABBV-075-treated human PBMC samples

PubMed ID

Publication Title

HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues.

Total Samples

10

Submitter’s Institution

Authors

Lin X, Huang X, Uziel T, Hessler P, Albert DH, Roberts-Rapp LA, McDaniel KF, Kati WM, Shen Y

Source Repository

Gene Expression Omnibus (GEO)

No rows found

Loading...