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SRP063496
Gene expression of baseline biopsies from etrolizumab-treated ulcerative colitis (UC) patients
Homo sapiens
73 Downloadable Samples
Illumina HiSeq 2000
Submitter Supplied Information
Description
RNA sequencing was performed on RNA isolated from baseline biopsies from UC patients enrolled in the Phase II EUCALYPTUS study of etrolizumab. Gene expression differences were identified in a subset of anti-TNF naïve patients that achieved clinical remission at 10 weeks in response to etrolizumab. Overall design: Baseline colonic biopsies from UC patients treated with etrolizumab were sequenced by the Illumina HiSeq 2000 Sequencing System.