RNA Sequencing analysis of different genetically characterized lung cancer cell lines

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SRP131516

Homo sapiens

36 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

We performed RNA sequencing to assess changes in gene expression in lung cancer cell lines with MET genetic alterations with or without co-occurrence of JAK2 inactivating mutations. Different treatments have been administrated to activate or inhibit selected pathways in order to define MET signature and IFNg (or JAK/STAT) signature. Overall design: Differential expression analysis of RNA sequencing of 4 different lung cancer cell lines with MET genetic alterations treated with different treatements to activate or inhibit selected pathways

PubMed ID

29898990

Publication Title

<i>MET</i>-Oncogenic and <i>JAK2</i>-Inactivating Alterations Are Independent Factors That Affect Regulation of PD-L1 Expression in Lung Cancer.

Total Samples

Submitter’s Institution

No associated institution

Authors

Saigi M, Alburquerque-Bejar JJ, Mc Leer-Florin A, Pereira C, Pros E, Romero OA, Baixeras N, Esteve-Codina A, Nadal E, Brambilla E, Sanchez-Cespedes M

Source Repository

Sequence Read Archive (SRA)

No rows found