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accession-icon GSE23820
Transcriptome analysis of CAX1/CAX3 double mutants
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

As part of a larger study on Cell-specific vacuolar calcium compartmentation regulates apoplastic calcium concentration, gas exchange and plant productivity we compared the transcriptome of 40day old CAX1/CAX3 double mutants to Col-0 wildtype plants.

Publication Title

Cell-specific vacuolar calcium storage mediated by CAX1 regulates apoplastic calcium concentration, gas exchange, and plant productivity in Arabidopsis.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE47881
Impact of resistance exercise on human skeletal muscle gene expression - ageing
  • organism-icon Homo sapiens
  • sample-icon 82 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The aim of this work was to produce a reproducible molecular signature of human muscle responses to resistance training and examine how such a profile relates to new and established exercise adaptation gene networks.

Publication Title

Molecular networks of human muscle adaptation to exercise and age.

Sample Metadata Fields

Age, Specimen part, Subject, Time

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accession-icon GSE47874
The Heritage (HEalth, RIsk factors, exercise Training And GEnetics) family study
  • organism-icon Homo sapiens
  • sample-icon 44 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The overall objective of the heritage project is to study the role of the genotype in cardiovascular,metabolic and hormonal responses to aerobic exercise training and the contribution of regular exercise to changes in several cardiovascular disease and diabetes risk factors.

Publication Title

Molecular networks of human muscle adaptation to exercise and age.

Sample Metadata Fields

Age, Specimen part, Subject, Time

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accession-icon GSE46498
Atrial Identity Is Determined by A COUP-TFII Regulatory Network
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Atrial identity is determined by a COUP-TFII regulatory network.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE46496
Atrial Identity Is Determined by A COUP-TFII Regulatory Network (RNA)
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Atria and ventricles exhibit distinct molecular profiles that produce structural and functional differences between the two cardiac compartments. However, factors that determine these differences remain largely undefined. Cardiomyocyte-specific COUP- TFII ablation produces ventricularized atria that exhibit ventricle-like action potentials, increased cardiomyocyte size, and development of extensive T-tubules.

Publication Title

Atrial identity is determined by a COUP-TFII regulatory network.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE17708
Time Course of TGF-beta treatment of A549 lung adenocarcinoma cell line
  • organism-icon Homo sapiens
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Time Course of TGF-beta treatment of A549 lung adenocarcinoma cell line on Affymetrix HG_U133_plus_2 arrays; triplicate experiments.

Publication Title

ConceptGen: a gene set enrichment and gene set relation mapping tool.

Sample Metadata Fields

Cell line

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accession-icon GSE73142
Blood, adipose and muscle samples taken from monozygotic twin pairs with age range 32-37
  • organism-icon Homo sapiens
  • sample-icon 61 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

FITFATTWIN study identified from the FinnTwin16 Cohort, which is a population based, longitudinal study of Finnish twins born between October 1974 and December 1979. The participants had no chronic disease affecting the ability to exercise, no acute disease, and no drug or alcohol abuse.

Publication Title

iGEMS: an integrated model for identification of alternative exon usage events.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE47969
Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT
  • organism-icon Homo sapiens
  • sample-icon 118 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The aim of this work was to compare the effects of AT, RT, and the full combination (AT/RT) on central ectopic fat, liver enzymes, and fasting insulin resistance [homeostatic model assessment (HOMA)]

Publication Title

A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.

Sample Metadata Fields

Age, Specimen part, Subject, Time

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accession-icon GSE48264
Uppsala Longitudinal Study of Adult Men (ULSAM)
  • organism-icon Homo sapiens
  • sample-icon 107 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [transcript (gene) version (huex10st)

Description

The Uppsala Longitudinal Study of Adult Men is a population-based study aimed at identifying risk factors for cardiovascular disease. At the time of biopsy all subjects were ~ 70yr of age

Publication Title

A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.

Sample Metadata Fields

Specimen part, Subject

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accession-icon GSE24142
Gene expression analysis of adult and fetal T-cell progenitors
  • organism-icon Mus musculus
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

Development of T-cells provides a unique opportunity to study cell-fate determination due to the accessability and the well defined stages of development. In order to understand the genetic programs underlying fetal and adult Tcell fate specification we subjected highly purified fetal and adult T-cell progenitor populations to a genomewide transcriptional analysis. The aim was to identify molecular elements that govern T-cell fate specification as a whole but ultimately to isolate elements that were specific for a given population in a specific developmental window.

Publication Title

Global transcriptional analysis of primitive thymocytes reveals accelerated dynamics of T cell specification in fetal stages.

Sample Metadata Fields

Sex

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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