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accession-icon GSE20193
Altered levels of MOF and decreased levels of H4K16ac correlate with a defective DNA damage response (DDR).
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Full title: Altered levels of MOF (member of MYST family histone acetyl transferase) and decreased levels of H4K16ac correlate with a defective DNA damage response (DDR).

Publication Title

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE33221
Conserved molecular interactions within MYST-ING acetyltransferase complexes that regulate cell proliferation
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

Sample Metadata Fields

Specimen part, Cell line, Treatment

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accession-icon GSE33220
Effects of the JADE-HBO1 complex on gene expression
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

We find that 499 genes are up-regulated and 457 are down-regulated in response to over-expression of JADE1, while 397 genes are up-regulated and 385 are down-regulated after HBO1 knock-down.

Publication Title

Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

Sample Metadata Fields

Cell line, Treatment

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