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accession-icon SRP128491
RNA-seq analysis of miR-324-5p overexpression upon H5N1 infection in A549 cells
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The goals of this study are to compare NGS-derived whole transcriptome profiles (RNA-seq) of H5N1 infected A549 cells overexpressing either negative control mimic or miR-324-5p mimic Overall design: A549 cells were either mock transfected or transfected with either negative control or mir-324-5p mimic. After 12 hours cells were either mock infected (mock transfected cells) or infected with A/duck/India/02CA10/2011 - H5N1 virus (negative control and miR-324-5p overexpressing cells)

Publication Title

MicroRNA hsa-miR-324-5p Suppresses H5N1 Virus Replication by Targeting the Viral PB1 and Host CUEDC2.

Sample Metadata Fields

Specimen part, Cell line, Subject

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accession-icon GSE61631
Comparative transcriptional profiling between the organs of the scion and rootstock of a homograft (Arabidopsis thaliana)
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Analyses of expression differences in flower bud and leaf of scion and rootstock, in homografts of Arabidopsis

Publication Title

Grafting triggers differential responses between scion and rootstock.

Sample Metadata Fields

Specimen part

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accession-icon GSE79867
Transcriptomic responses of the liver and adipose tissues to altered carbohydrate-fat ratio in diet: An isoenergetic study in young rats
  • organism-icon Rattus norvegicus
  • sample-icon 31 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Genome 230 2.0 Array (rat2302)

Description

To elucidate the effects of altered dietary carbohydrate and fat balance on liver and adipose tissue transcriptomes,

Publication Title

Transcriptomic responses of the liver and adipose tissues to altered carbohydrate-fat ratio in diet: an isoenergetic study in young rats.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE106766
Short-term mastication after weaning upregulates GABAergic signalling and reduces dendritic spine in thalamus
  • organism-icon Rattus norvegicus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Genome 230 2.0 Array (rat2302)

Description

Mastication enhances brain function and even mental health, but little is known molecular basis underlying the effects of chewing on neural development in early childhood we conducted experiment with rats fed a with soft or hard chow diet immediately after weaning and investigated the expression of genes were investigated after another 8 days of breeding.

Publication Title

Short-term mastication after weaning upregulates GABAergic signalling and reduces dendritic spine in thalamus.

Sample Metadata Fields

Sex, Age

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accession-icon GSE18285
Characterization of the transcriptional roles of NME2
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Non-metastatic 2 (NME2)-mediated suppression of lung cancer metastasis involves transcriptional regulation of key cell adhesion factor vinculin.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE38490
Comparative analysis of transcriptome profiles of G. hirsutum L. cv. MCU5 and its fuzzless-lintless mutant during fiber development stages.
  • organism-icon Gossypium hirsutum
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Cotton Genome Array (cotton)

Description

Cotton is one of the most commercially important Fiber crops in the world and used as a source for natural textile Fiber and cottonseed oil. The fuzzless-lintless ovules of cotton mutants are ideal source for identifying genes involved in Fiber development by comparing with Fiber bearing ovules of wild-type. To decipher molecular mechanisms involved in Fiber cell development, transcriptome analysis has been carried out by comparing G. hirsutum cv. MCU5 (wild-type) with its fuzzless-lintless mutant (MUT). Cotton bolls were collected at Fiber initiation (0 dpa/days post anthesis), elongation (5, 10 and 15 dpa) and secondary cell wall synthesis stage (20 dpa) and gene expression profiles were analyzed in wild-type and MUT using Affymetrix cotton GeneChip Genome array.

Publication Title

Functional genomics of fuzzless-lintless mutant of Gossypium hirsutum L. cv. MCU5 reveal key genes and pathways involved in cotton fibre initiation and elongation.

Sample Metadata Fields

Specimen part

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accession-icon GSE29810
Global gene expression analysis of cotton (Gossypium hirsutum L.) under drought stress in leaf tissue and during fibre development stages.
  • organism-icon Gossypium hirsutum
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Cotton Genome Array (cotton)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Genome-wide transcriptomic analysis of cotton under drought stress reveal significant down-regulation of genes and pathways involved in fibre elongation and up-regulation of defense responsive genes.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE29567
Global gene expression analysis of cotton (Gossypium hirsutum L.) under drought stress during fibre development stages.
  • organism-icon Gossypium hirsutum
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Cotton Genome Array (cotton)

Description

Transcriptome analysis in cotton during fibre development stages.

Publication Title

Genome-wide transcriptomic analysis of cotton under drought stress reveal significant down-regulation of genes and pathways involved in fibre elongation and up-regulation of defense responsive genes.

Sample Metadata Fields

Treatment

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accession-icon GSE29566
Global gene expression analysis of cotton (Gossypium hirsutum L.) under drought stress in leaf tissue.
  • organism-icon Gossypium hirsutum
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Cotton Genome Array (cotton)

Description

Transcriptome analysis in cotton under drought stress.

Publication Title

Genome-wide transcriptomic analysis of cotton under drought stress reveal significant down-regulation of genes and pathways involved in fibre elongation and up-regulation of defense responsive genes.

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE56936
Expression data from NEAT1 regulated genes with or without polyI:C
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Although thousands of long non-coding RNAs (lncRNAs) are localized in the nucleus, only a few dozen have been functionally characterized.

Publication Title

Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.

Sample Metadata Fields

Cell line

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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