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accession-icon GSE31434
Expression data from HeLa cells transfected with SLC44A5
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We identified SLC44A5 as a gene associated with birth weight in cattle based on genome wide association studies.

Publication Title

The molecular effects of a polymorphism in the 5'UTR of solute carrier family 44, member 5 that is associated with birth weight in Holsteins.

Sample Metadata Fields

Cell line

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accession-icon GSE50738
Expression data from human induced pluripotent stem cells derived retinal pigment epithelium (hiPSC-RPE)
  • organism-icon Homo sapiens
  • sample-icon 39 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We generated hiPSCs from patients fibloblast with retinitis pigmentosa (RP) using retrovirus and Sendai virus vectors, which we differentiated into hiPSC derived retinal pigment epithelium using two different methods (SDIA and SFEB methods).

Publication Title

Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application.

Sample Metadata Fields

Cell line

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accession-icon GSE5231
IGF1R Mediates Mammalian Immune Function in Response to FEZL
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE5225
Expression data from OCUBM cells trasfected with IGF1R
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To investigate genes that might influence resistance to infection through IGF1R, we screened human breast cancer-derived OCUB-M cells transfected with expression vector encoding IGF1R using microarray analysis.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE5224
Expression data from OCUBM cells trasfected with 12G FEZL
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To identify genes that influence resistance to mastitis, we scanned

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE4342
Gefitinib sensitivity in NSCLC cell lines
  • organism-icon Homo sapiens
  • sample-icon 45 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Eleven NSCLC cell lines with widely divergent gefitinib sensitivities were compared using gene expression. Genes associated with gefitinib response were used to classify additional NSCLC lines with unknown gefitnib sensitivity.

Publication Title

Baseline gene expression predicts sensitivity to gefitinib in non-small cell lung cancer cell lines.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE83196
Beta-catenin-regulated genes in pancreatic cancer cells
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Activation of the canonical Wnt signaling pathway is commonly observed in pancreatic cancer. We therefore sought to identify a gene expression profile associated with the activation of this pathway in pancreatic cancer cells.

Publication Title

Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE28447
Expression data from transgenic mice overexpressing RXR-gamma in the skeletal muscle (RXR-gamma mice)
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Retinoid X receptor (RXR)-gamma is a nuclear receptor-type transcription factor expressed mostly in the skeletal muscle, and regulated by nutritional conditions. Previously, we established transgenic mice overexpressing RXR-gamma in the skeletal muscle (RXR-gamma mice), which showed lower blood glucose than the control mice. We used microarrays to investigate their glucose metabolism gene expression change.

Publication Title

Increased systemic glucose tolerance with increased muscle glucose uptake in transgenic mice overexpressing RXRγ in skeletal muscle.

Sample Metadata Fields

Sex, Age

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accession-icon GSE10216
Emx2 knock-out urogenital epithelium
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Series of samples studying effect of knock out Emx2 in urogenital epithelium of mouse embryos at E10.5.

Publication Title

Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor (EGFR) expression induced in Emx2 KO embryonic gonads.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE28856
Expression data of wild-type C. elegans shifted from 23 degrees to 17 degrees
  • organism-icon Caenorhabditis elegans
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix C. elegans Genome Array (celegans)

Description

C. elegans exhibits thermotaxis, where most of the animals that had been cultivated at a particular temperature ranging from 15C to 25C for a few hours with a food source and then placed on a thermal gradient for an hour migrate to the cultivation temperature. In addition, animals that were previously conditioned to migrate to a certain temperature are capable of migrating to a new cultivation temperature a few hours after the cultivation temperature was shifted to the new temperature

Publication Title

Regulation of behavioral plasticity by systemic temperature signaling in Caenorhabditis elegans.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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