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accession-icon SRP064897
lung tissue of pigs Transcriptome or Gene expression
  • organism-icon Sus scrofa
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

the mRNA expression of pig lung tissue. there are four groups: LW pigs infected with PCV2, LW pigs control, Yorkshire × Landrace (YL) pigs infected with PCV2, Yorkshire × Landrace (YL) pigs control.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage, Cell line, Treatment

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accession-icon SRP090540
Danio rerio strain:AB Raw sequence reads
  • organism-icon Danio rerio
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIlluminaHiSeq4000

Description

Identification of circular RNAs in zebrafish

Publication Title

Identification and characterization of circular RNAs in zebrafish.

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP139292
miR-218
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Small RNA seq following over expression of miR-218 in HepG2 cells; mRNA expression following perturbation of miR-218 in primary mouse motor neurons

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon SRP114906
Transcriptomic analysis of progranulin-deficienct mouse brains
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Progranulin mutations found in frontotemporal lobar degeneration (FTLD) cases typically result in heterozygous loss-of-function. To assess the impact of PGRN deficiency on gene expression, particularly of genes associated with lipid metabolism, in the brain, we sequenced the total RNA extracted from whole brains from 7-month-old female Grn+/+, Grn+/–, and Grn–/– mice and determined the differential expression of transcripts in PRGN-deficient (Grn+/- and Grn-/-) and wild type (Grn+/+) brains.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line

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accession-icon SRP092744
Genes and polymorphism identification associated to hernias in swine
  • organism-icon Sus scrofa
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Transcriptome of connective tissue of swine affected and non-affected with scrotal hernia

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease

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accession-icon ERP005567
Generation of a de novo trascriptome assembly from equine lamellar tissue
  • organism-icon Equus caballus
  • sample-icon 3 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

The equine hoof is a specialized structure in which the distal skeleton is suspended within the capsule by interdigitated structures known as laminae. Inflammation of this tissue, known as laminitis, is a devastating disease that is the second leading cause of both lameness and euthanasia in the horse. Current research on the laminitic transcriptome focuses on the expression of known genes. However, as this tissue is quite unique and equine annotation is largely derived from computational predictions and gene models from other species, there are likely yet uncharacterized transcripts expressed in the laminae that may be involved in the etiology of laminitis. In order to create a novel annotation resource, we performed whole transcriptome sequencing of sagittal lamellar sections from one control and two laminitis affected horses. Assembly of 113 million 100bp reads resulted in around 75,000 transcripts. Of these, 36,000 corresponded to known annotation in NCBI's non-redundant protein database. RT-PCR of 12 selected annotations confirmed structure and expression in lamellar tissue. Transcriptome sequencing represents a powerful tool to expand on equine annotation and identify novel targets for further laminitis research.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon E-MEXP-1138
Transcription profiling of mature pollen grains from wild type and AtMIKC* MADS-box gene knock-out Arabidopsis plants
  • organism-icon Arabidopsis thaliana
  • sample-icon 28 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Effects of loss-of-function of AtMIKC* MADS-box genes on the mature Arabidopsis pollen transcriptome.

Publication Title

MADS-complexes regulate transcriptome dynamics during pollen maturation.

Sample Metadata Fields

Age, Specimen part

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accession-icon SRP075626
Mycobacterial infection of adult zebrafish
  • organism-icon Danio rerio
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

RNA-seq-based profiling of Mycobacterium marinum granulomas from adult zebrafish and matched macrophage samples.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP035483
Bos taurus strain:Hanwoo Transcriptome or Gene expression
  • organism-icon Bos taurus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2000

Description

Although it is well known that the function of MyoG cannot be compensated for other MRFs, the molecular mechanism by which MyoG controls muscle cell differentiation is still unclear. Therefore, in this study, RNA-Seq technology was applied to profile changes in gene expression in response to MyoG knock-down (MyoGkd) in primary bovine muscle satellite cells (MSCs). This study is the first RNA-Seq based gene expression analysis of MyoGkd undertaken in primary bovine MSCs.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease

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accession-icon SRP113626
Saccharomyces cerevisiae RNAseq Raw sequence reads
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 338 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

WT cells and mutants during growth on low phosphate levels and recovery

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Disease, Cell line

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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