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accession-icon GSE56062
Expression data from internodes of maize seedlings
  • organism-icon Zea mays
  • sample-icon 14 Downloadable Samples
  • Technology Badge Icon Affymetrix Maize Genome Array (maize)

Description

Plant growth regulators (PGRs) were commonly used in practical farming to restrict plant height and control lodging. Ethephon has been reported to shorten the internodes elongation and increase the harvestable grain yield of maize. In the present study, we characterized that internodes phenotypic responses to ethephon treatment induced should due to ethylene released inhibited the longitudinal growth of cells and promoted its the lateral growth.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon E-MTAB-2553
Transcription profiling by array of Arabidopsis MKK9DD (constitutively active MKK9 kinase mutant) overexpressing seedlings and Pi-starved wild type seedlings to identify the same regulated genes
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Transcription profiling by array of Arabidopsis MKK9DD (constitutively active MKK9 kinase mutant) overexpressing seedlings and Pi-starved wild type seedlings to identify the same regulated genes

Publication Title

Activation of MKK9-MPK3/MPK6 enhances phosphate acquisition in Arabidopsis thaliana.

Sample Metadata Fields

Specimen part, Compound

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accession-icon GSE12675
Hypoxia effect on embryonic hearts of Tibetan Chicken, Dwarf Recessive White Chicken and Shouguang Chicken
  • organism-icon Gallus gallus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Adaptation to hypoxia is a complicated and important physiological course for organisms, but the genetic mechanism underlying the adaptation is not fully understood yet. Tibetan Chicken (T), an indigenous chicken breed in China which inhabit in high areas with an altitude above 2,900 meters. Shouguang Chicken(S) and Dwarf Recessive White Chicken (DRW), two lowland chicken breeds, were used as control groups. The heart was the first functional organ to develop during the embryonic development. Furthermore, the heart is an efficient energy converter utilizing the most appropriate fuel for a given environment. Therefore, GeneChip Chicken Genome Array was employed to identify the differentially expressed genes in embryonic hearts of Tibetan Chicken and two lowland chicken breeds in both hypoxic and normoxic incubating environments with a genome wide profile.

Publication Title

Study on Tibetan Chicken embryonic adaptability to chronic hypoxia by revealing differential gene expression in heart tissue.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE30735
Transcriptome Analysis of hub2-3 vs the wild-type Col
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

HUB2 had been previously identified as a H2B monoubiquitinating E3 ligase. Loss of HUB2 leads to a pleiotropic phenotype, including reduced seed dormancy, smaller plant size and early flowering. Microarray expression profiling was used to identify differentially expressed genes between hub2-3 mutant and wild-type Col seedlings.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE6696
Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Pollen germination, along with pollen tube growth, is an essential process for the reproduction of flowering plants. The germinating pollen with tip-growth characteristics provides an ideal model system for the study of cell growth and morphogenesis. As an essential step towards a detailed understanding of this important process, the objective of this study was to comprehensively analyze the transcriptome changes during pollen germination and pollen tube growth. Using Affymetrix Arabidopsis ATH1 Genome Arrays, this study is the first to show the changes in the transcriptome from desiccated mature pollen grains to hydrated pollen grains and then to pollen tubes of Arabidopsis thaliana. The number of expressed genes, either for total expressed genes or for specifically expressed genes, increased significantly from desiccated mature pollen to hydrated pollen and again to growing pollen tubes, which is consistent with the finding that pollen germination and tube growth was significantly inhibited in vitro by a transcriptional inhibitor. The results of GO analyses showed that expression of genes related to cell rescue, transcription, signal transduction and cellular transport were significantly changed, especially for up-regulation, during pollen germination and tube growth, respectively. In particular, genes of the CaM/CML, CHX and Hsp families showed the most significant changes during pollen germination and tube growth. These results demonstrate that the overall transcription of genes, both in the number of expressed genes and in the levels of transcription, was increased. Furthermore, the appearance of many novel transcripts during pollen germination as well as tube growth indicates that these newly expressed genes may function in this complex process.

Publication Title

Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE45710
Expression data from subcutaneous adipose tissue of barrows and boars
  • organism-icon Sus scrofa
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

The male hypogonadism is closely associated with adipose tissue metabolism. Domestic pig has been a widely used experimental animal in biomedical research because of their similarity to humans in body size and other physiological/anatomical features. However, the transcriptional responses of pigs to male hypogonadism in subcutaneous adipose tissue remain unclear so far.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE13786
Gene expression profiling in Chinese mininature pig liver tissue following clenbuterol administration
  • organism-icon Sus scrofa
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

Clenbuterol-HCL can greatly reduce fat deposition and increase skeletal muscle growth at high dosages. In order to advance our understanding of the fundamental molecular mechanisms, Genechips were used to study the differential gene expression profiles of liver tissues among the pigs with/without Clenbuterol-HCL. Differentially expressed genes identified will be the candidates for further investigations on the molecular mechanisms involved in Clenbuterol-HCL of exerting repartition effects on adipose and skeletal muscle tissue.

Publication Title

Identifying lipid metabolism genes in pig liver after clenbuterol administration.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE60351
Expression data from wheat cultivar TAM 107 flag leaf
  • organism-icon Triticum aestivum
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Wheat Genome Array (wheat)

Description

We used microarray to study the transcriptome response of wheat flag leaves to heat stress (40)

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE18273
Comparison of gene expression regulated by WRKY6
  • organism-icon Arabidopsis thaliana
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

WRKY6-overexpressing line 35S:WRKY6-9, knockout mutant wrky6-1 and wild-type seedlings were used to analyze genes whose expression are controlled under WRKY6.

Publication Title

The WRKY6 transcription factor modulates PHOSPHATE1 expression in response to low Pi stress in Arabidopsis.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE23592
Gene Expression Profiling of Three Tissues in Chicken with Heat Stress by Affymetrix Microarray
  • organism-icon Gallus gallus
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Heat stress is a very complex physiological process. At present, there are some reports about physiological function and pathological changed on chicken heat stress.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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