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accession-icon GSE13203
Global transcriptional profiling of Staphylococcus aureus treated with cryptotanshinone
  • organism-icon Staphylococcus aureus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Cryptotanshinone, a natural plant product, has potent antimicrobial activity against S. aureus.

Publication Title

Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cryptotanshinone.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE13233
Global transcriptional profiling of Staphylococcus aureus treated with sodium houttuyfonate
  • organism-icon Staphylococcus aureus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. sodium houttuyfonate has potent antimicrobial activity against S. aureus.

Publication Title

Transcriptional and functional analysis shows sodium houttuyfonate-mediated inhibition of autolysis in Staphylococcus aureus.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE13236
Global transcriptional profiling of Staphylococcus aureus treated with magnolol
  • organism-icon Staphylococcus aureus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. magnolol has potent antimicrobial activity against S. aureus.

Publication Title

Transcriptional and functional analysis of the effects of magnolol: inhibition of autolysis and biofilms in Staphylococcus aureus.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE7944
Global transcriptional profiling of Staphylococcus aureus treated with berberine chloride
  • organism-icon Staphylococcus aureus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Berberine chloride (BBR), a natural plant product, has potent antimicrobial activity against S. aureus.

Publication Title

Global transcriptional profiles of Staphylococcus aureus treated with berberine chloride.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE8135
Global transcriptional profiling of Staphylococcus aureus treated with rhein
  • organism-icon Staphylococcus aureus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus is one of the most important pathogens in humans and animals, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Rhein, a natural plant product, has potential antimicrobial activity against Staphylococcus aureus.

Publication Title

Global transcriptional response of Staphylococcus aureus to rhein, a natural plant product.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE8735
Global transcriptional profiling of Staphylococcus aureus treated with eugenol
  • organism-icon Staphylococcus aureus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. eugenol, a natural plant product, has potent antimicrobial activity against S. aureus.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE59226
Expression data from Human Umbilical Vein Endothelial Cell after influenza virus infection
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This research focus primarily on the interaction between influenza virus and endothelial cell, then we used microarrays to observe global patterns of gene expression in Human Umbilical Vein Endothelial Cells after influenza virus infection and offer further insight into the interaction between endothelial cells and influenza viruses.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon SRP212839
Epididymis of mice infected with Toxoplasma gondii
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Toxoplasma infection can cause damage to the male reproductive system, such as sexual dysfunction and infertility. The epididymis is an important accessory organ of male reproductive system, where sperm maturation and storage take place. Sperm maturation in the epididymis is a highly programmed process, which may be affected by the epididymis microenvironment. Therefore, studying the epididymis characteristics is important for identification of factors affecting sperm maturation. However, studies investigating the differential expression genes of host and Toxoplasma gondii by transcriptome sequencing of the male reproductive system are limited. The main objective of this study was to examine differential gene expression by RNA sequencing (RNA-seq) technology in order to identify key genes associated with Toxoplasma gondii (PRU strain) chronic infection of the epididymis in male Kunming mice.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line

View Samples
accession-icon SRP039377
The Transcriptomes of Natural Developmental Magnum in Chickens
  • organism-icon Gallus gallus
  • sample-icon 7 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

The goal of this study is to obtain the transcriptomes of chicken magnum in different natural developmental stages. There are totally five stages researched in this study and they are named D1, D2, D3, D4 and L. D1 to D4 are the abbreviations of developmental stage 1 to developmental stage 4 and L means laying stage. D1 refers to the lag phase (about 7 weeks old) in which the magnum has very slight change; D2 refers to the early proliferation phase (about 13 weeks old); D3 refers to the late proliferation phase (about 16 weeks old); D4 refers to the early differentiation phase (about 17 weeks old).

Publication Title

No associated publication

Sample Metadata Fields

Age

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accession-icon SRP144529
Gallus gallus Transcriptome or Gene expression
  • organism-icon Gallus gallus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

In the experiment, we took a chinese chicken with different body weights at 300 days as the research subjects. The chickens were divided into fast- and slow-growing groups (high body weight and low body weight). We selected leg muscles after slaughtering and used then for RNA-seq. Finally, we screened differentially expressed genes and the corresponding enriched pathways related to growth through a bioinformatics analysis. The results provide a theoretical foundation for revealing the molecular mechanism of the growth for chickens and improving the production performance of the Jinghai yellow chicken.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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