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accession-icon GSE136835
Change in cellular mRNA expression caused by US7 or US8
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.0 ST Array (hugene20st)

Description

HCMV glycoproteins US7 and US8 target the innate immune response.

Publication Title

HCMV-encoded US7 and US8 act as antagonists of innate immunity by distinctively targeting TLR-signaling pathways.

Sample Metadata Fields

Specimen part

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accession-icon GSE43497
Effector cell signatures in peripheral blood after nasal allergen challenge: biomarkers of the allergic response
  • organism-icon Homo sapiens
  • sample-icon 190 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

This study investigated temporal transcriptomic changes in response to nasal allergen challenge of titrated timothy grass pollen.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Time

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accession-icon GSE118587
Expression data for participants in iWITH study at screening visit
  • organism-icon Homo sapiens
  • sample-icon 132 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U219 Array (hgu219)

Description

A cross sectional study using data collected at the time of liver biopsy, the final eligibility assessment for participation in iWITH (NCT01638559), an immunosuppression withdrawal trial.

Publication Title

Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants.

Sample Metadata Fields

Specimen part

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accession-icon GSE22229
Identification of a B cell signature associated with renal transplant Tolerance in humans
  • organism-icon Homo sapiens
  • sample-icon 55 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

In this study, investigators recruited the largest reported cohort of tolerant kidney transplant recipients who maintained their graft after ceasing to take their immunosuppression drug, and compared this cohort to subjects with stable allograft function while on immunosuppression and healthy non transplated, controls. Using gene expression studies, they identified genetic markers that are strong candidates for predicting kidney transplant candidates who may benefit from minimization or withdrawl of immunosuppression.

Publication Title

Identification of a B cell signature associated with renal transplant tolerance in humans.

Sample Metadata Fields

Specimen part

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accession-icon GSE16674
Analysis of gene expression in miR-34a overexpressing K562 cells
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

miR-34a is strongly induced upon TPA-induced megakaryocyte differentiation of K562 cells. To investigate the gene networks regulated by this miRNA during the process of differentiation we performed gene microarray analysis in K562 cells overexpressing miR-34a or a control sequence.

Publication Title

miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53.

Sample Metadata Fields

Cell line

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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